Publications by authors named "F Franconi"

The authors report a case of a sexual serial killer responsible for four homicides (one homosexual and three prostitutes) over a 12-year period. The perpetrator was diagnosed with a severe personality disorder and necrophilia at the time of the crimes and was declared partially mentally impaired and dangerous to societal security by the Court of Jurisdiction for these crimes. The offender served 22 years in prison, including half of the detention in an OPG (High Security Forensic Psychiatry Hospital) receiving psychiatric treatment.

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MRI is widely used for the detection and characterization of brain lesions. There is a growing interest in the potential benefits of quantitative MRI (qMRI) in veterinary brain lesion diagnosis. Yet, the use of data processing tools in the veterinary field is not as democratized as for the diagnosis of human brain pathologies.

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Article Synopsis
  • Research indicates that sex-gender differences can affect how men and women respond to medications for neuropathic pain, with women generally achieving higher blood levels and experiencing more side effects.
  • A limited number of studies have explored these differences specifically in neuropathic pain treatments, with most focusing instead on other conditions like depression.
  • To improve treatment outcomes for the 60% of neuropathic pain patients who don't respond adequately to medications, further targeted research is essential to understand these sex-gender differences better and enable personalized treatment approaches.
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Aims: To investigate whether the risk for post-partum cardiovascular diseases (CVD) is driven by gestational diabetes (GDM), by GDM-related risk factors and/or by pre-gestational (Pre-GD) or post-gestational diabetes (Post-GD).

Methods: Women delivering in Tuscany, Italy in years 2010-2012 (n = 74,720), were identified from certificates of care at delivery and further identified as affected with GDM, Pre-GD or Post-GD through regional administrative databases. Women with GDM, Pre-GD or Post-GD were retrospectively evaluated for risk of post-partum hospitalizations for CVD (myocardial infarction or stroke; n = 728) across years 2013-2021, comparing women with different forms of diabetes to those without diabetes.

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Until now, research has been performed mainly in men, with a low recruitment of women; consequentially, biological, physiological, and physio-pathological mechanisms are less understood in women. Obviously, without data obtained on women, it is impossible to apply the results of research appropriately to women. This issue also applies to medical devices (MDs), and numerous problems linked to scarce pre-market research and clinical trials on MDs were evidenced after their introduction to the market.

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