Publications by authors named "F Fourrier"

Background And Objectives: A postauthorization safety study was performed between 2009 and 2012 to describe the use of Clottafact in acquired fibrinogen deficiency in real-life medical practice in France.

Materials And Methods: One hundred and fifty patients were planned for 28 days of prospective follow-up after infusion. The analysis of this observational study was descriptive and performed according to the type of treatment (curative or preventive) and the origin of the bleed.

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Purpose: Data for ANCA-associated vasculitis (AAV) patients requiring intensive care are scarce.

Methods: We included 97 consecutive patients with acute AAV manifestations (new onset or relapsing disease), admitted to 18 intensive care units (ICUs) over a 10-year period (2002-2012). A group of 95 consecutive AAV patients with new onset or relapsing disease, admitted to two nephrology departments with acute vasculitis manifestations, constituted the control group.

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Article Synopsis
  • The study aimed to compare two diagnostic scores for disseminated intravascular coagulation (DIC) in pregnant women who experienced severe complications during or after delivery in the ICU.
  • A new score, tailored to pregnancy-related physiological changes, showed significantly better sensitivity and specificity compared to the International Society for Thrombosis and Hemostasis (ISTH) score, which had notably lower sensitivity.
  • The findings suggest that the new DIC score is more effective for diagnosing DIC in postpartum patients, while the ISTH score should not be used in pregnant women due to its inadequate sensitivity.
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Evidence-based medicine criticism. Evidence-based medicine is now considered as the rule in the practice of clinical medicine. It covers however a lot of issues and limitations, leading to numerous and severe pitfalls.

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