Publications by authors named "F Fortune"
Introduction: Crohn's disease (CD) is a chronic inflammatory bowel disease which can affect any area of the gastrointestinal tract, including oral tissues. The complex nature of this disease demands interdisciplinary management, especially when both intestinal and oral manifestations are present.
Case: This report presents the case of a 28-year-old male patient with oral, ileo-caecal and peri-anal CD managed jointly between Gastroenterology and Oral Medicine.
Objectives: To explore the demographic and clinical profile of erosive lichen planus (ELP) across multiple ethnicities within a single cohort, deepening our understanding of disease severity, progression and outcomes.
Methods: A longitudinal retrospective cohort study of ELP patients in the ethnically diverse population of East London was carried out, profiling ELP ( = 57) against the milder reticular lichen planus (RLP) ( = 35).
Results: A higher prevalence of ELP was observed in white populations compared to other ethnicities.
Article Synopsis
- Rapid urbanization in sub-Saharan Africa is linked to a rise in asthma cases among children and teens, particularly due to challenges in obtaining clinical diagnoses for those exhibiting symptoms.* -
- A two-phase study was conducted across multiple countries involving adolescents aged 12-14, where asthma symptoms were assessed through a questionnaire, and further evaluations were carried out on those with symptoms, including tests for lung function and environmental risk factors.* -
- The study aimed to gather data on the prevalence and severity of asthma in symptomatic adolescents, alongside objective testing methods like spirometry and fractional exhaled nitric oxide (FeNO) to better understand asthma's impact on daily life.*
Objectives: Whilst biologic therapy is used for Behçet's Syndrome of all subtypes refractory to first-line immunomodulation, there has been an absence of high-quality evidence-and no predictive biomarkers to optimally inform choice. BIO-BEHÇET'S was a randomised, controlled, head-to-head clinical trial comparing the two most frequently used biologics in active refractory Behçet's.
Methods: Bayesian-designed, pragmatic, standard of care, two-arm, parallel head-to-head trial at four UK centres.
Article Synopsis
- * It included 116 patients with pSS, assessing salivary flow rates, eye dryness, and psychological health using various patient-reported outcome measures like the Brief Resilience Scale (BRS) and the Hospital Anxiety and Depression Scale (HADS).
- * Findings indicated lower resilience scores in patients experiencing recurrent parotitis, and those with both dry mouth and dry eyes, suggesting these factors, along with anxiety and depression, may negatively influence psychological resilience in pSS patients.