Publications by authors named "F Fortarezza"
Hidradenocarcinoma (HAC) is a rare malignant neoplasm originating from eccrine sweat glands, often presenting diagnostic challenges because of its resemblance to other malignancies, particularly breast cancer when occurring in the chest region. This report describes 2 cases of HAC with axillary lymph node metastasis, both initially misinterpreted clinically. The first case involved a 63-year-old woman with a sternal mass, near the right breast, initially suspected to be a sebaceous cyst.
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- - Giant cell interstitial pneumonia (GIP) is a serious lung disease related to exposure to hard metals like tungsten, typically found in industrial tools, but it can also occur without clear exposure history.
- - In a study of five patients with GIP, researchers used advanced techniques to identify metal dust and asbestos in lung samples, finding trace amounts of tungsten and asbestos fibers associated with severe lung damage.
- - The results suggest that other factors beyond hard metal exposure might contribute to GIP's development, hinting at a complex immune mechanism that could explain its recurrence in lung transplants.
Article Synopsis
- Pathology is essential for accurately diagnosing skin tumors, which is important for creating tailored treatment plans and improving patient care in dermatology.
- The updated WHO classification of skin tumors includes new sections on nail unit tumors, skin metastases, and genetic syndromes, alongside advancements in understanding various skin tumors on molecular levels.
- Recent findings, particularly regarding melanocytic tumors, have led to new terminology and an integrated diagnostic approach that emphasizes morphology, immunohistochemistry, and molecular features, aiding clinical decision-making and fostering collaboration in treatment development.
Chronic Obstructive Pulmonary Disease (COPD) and lung cancer are strictly related. To date, it is unknown if COPD-associated cancers are different from the tumors of non-COPD patients. The main goal of the study was to compare the morphological/molecular profiles of lung adenocarcinoma (LUAD) samples of COPD, non-COPD/smokers and non-COPD/non-smokers, and to investigate if a genetic instability also characterized non-pathological areas.
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- The diagnosis of herpes zoster (HZ) can be complicated by atypical histological presentations that don’t show the usual viral changes.
- The review focuses on the existing research around these atypical skin manifestations and highlights the importance of recognizing subtle hints in the histology.
- Techniques like immunohistochemistry are discussed to aid in accurate diagnosis, along with common mistakes that can occur in this process.