Major mite allergen Der f 1 concentration is reduced in buildings with improved energy performance.

Background: Environmental conditions play a crucial role in mite growth, and optimal environmental control is key in the prevention of airway inflammation in chronic allergic rhinoconjunctivitis or asthma.

Objective: To evaluate the relationship between building energy performance and indoor mite allergen concentration in a cross-sectional study.

Methods: Major allergen concentration (Der f 1, Der p 1, mite group 2, Fel d 1 and Bla g 2) was determined by quantitative dot blot analysis from mattress and carpet dust samples in five buildings designed for low energy use (LEB) and in six control buildings (CB).