Publications by authors named "F Foldes"
Background/objectives: The ongoing COVID-19 pandemic has underscored the need for alternative prophylactic measures, particularly for populations for whom vaccines may not be effective or accessible. This study aims to evaluate the efficacy of intranasally administered IgY antibodies derived from hen egg yolks as a protective agent against SARS-CoV-2 infection in Syrian golden hamsters, a well-established animal model for COVID-19.
Methods: Hens were immunized with the spike protein of SARS-CoV-2 to generate IgY antibodies.
This study aims to highlight the importance of choosing the appropriate co-polymer or co-polymer mixed combinations in order to design value-added nasal dosage forms. Local therapy of upper respiratory tract-related infections, such as nasal rhinosinusitis is of paramount importance, thus advanced local therapeutic options are required. Dexamethasone was encapsulated into three different polymeric micelle formulations: Soluplus or TPGS-only and their mixed combinations.
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- * In a 2021 study, researchers sequenced the viral metagenome of a Hyalomma marginatum tick and discovered the Volzhskoe tick virus, which is part of the unclassified Bunyaviricetes group.
- * The analysis revealed important genetic information and showed that the Volzhskoe tick virus is related to other unclassified species found in diverse locations, highlighting the need for more research on its potential health impacts and
Lloviu cuevavirus (LLOV) was the first identified member of Filoviridae family outside the Ebola and Marburgvirus genera. A massive die-off of Schreibers's bats (Miniopterus schreibersii) in the Iberian Peninsula in 2002 led to its initial discovery. Recent studies with recombinant and wild-type LLOV isolates confirmed the zoonotic nature of the virus in vitro.
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- - The recent Monkeypox outbreak highlights the need for research on the basic biology of orthopoxviruses, as it hasn’t been thoroughly studied before.
- - This study uses Oxford Nanopore long-read RNA-Sequencing to analyze the transcriptome of the monkeypox virus, addressing a significant gap in research.
- - By analyzing direct cDNA and native RNA sequencing reads, the research aims to reveal changes in gene expression for both the monkeypox virus and its host during infection, leading to a better understanding of transcriptomic alterations caused by the virus.