Publications by authors named "F Fobe"
Article Synopsis
- The study investigated how variations in the CYP2D6 gene affect the body’s response to tramadol and its active form, O-dT, in European adult patients after surgery.
- Researchers classified participants' CYP2D6 metabolizer types (EM, IM, PM, UM) and measured the O-dT/T ratio in their plasma to see if it could effectively indicate their CYP2D6 phenotype.
- Results showed that while the O-dT/T ratio was lower in poor metabolizers (PM) compared to non-PM, there was significant overlap between groups, indicating that tramadol is not a reliable drug for accurately determining CYP2D6 phenotypes.
Background: The aim of this study was to investigate whether the implementation of enhanced recovery after surgery (ERAS) guidelines according to Thorell and co. in our tertiary referral bariatric center might improve post-operative outcomes.
Methods: ERAS program was introduced in our center since January 1, 2017.
An uncommon electrocardiographic change in subarachnoid hemorrhage: increase in the Sokolow's Index.
J Neurosurg Anesthesiol
April 1992
In this paper we are reporting a case of electrical left ventricular hypertrophy with increased Sokolow's index following subarachnoid hemorrhage. Two-dimensional echocardiography ruled out anatomical left ventricular hypertrophy, and the Sokolow's index eventually reverted to normal. This electrocardiographic abnormality has rarely been associated with subarachnoid hemorrhage and does not appear to be related to the neurologic grade of the patient because he presented with headaches only and was conscious throughout (Hunt and Hess grade I).
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