Publications by authors named "F Fieux"
Background: In intensive care units, patients are frequently unable to take oral drugs because of orotracheal intubation or sedation.
Local Problem: Adverse events occurred during the administration of drugs by feeding tube. This study assessed the impact of implementing good practice guidelines by a clinical pharmacist on the prescription and administration of drugs through feeding tubes.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to 5% to 16% hospitalization in intensive care units (ICU) and is associated with 23% to 75% of kidney impairments, including acute kidney injury (AKI). The current work aims to precisely characterize the renal impairment associated to SARS-CoV-2 in ICU patients. Forty-two patients consecutively admitted to the ICU of a French university hospital who tested positive for SARS-CoV-2 between 25 March 2020, and 29 April 2020, were included and classified in categories according to their renal function.
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- * Researchers evaluated 101 patients over six weeks, analyzing plasma biomarkers to see how they correlated with organ failure severity and mortality rates after 60 days.
- * Key findings revealed that higher levels of IL-6 and CRP were associated with worse outcomes and increased mortality, whereas changes in IL-6 levels over time did not correlate with mortality; instead, CRP levels and lymphocyte counts showed different patterns between survivors and non-survivors.