Publications by authors named "F Fernandez-Fuertes"
Article Synopsis
- Immune thrombocytopenia (ITP) is a prevalent autoimmune disorder that presents diagnostic challenges due to varied symptoms and no specific test available.
- Recent research and new medications have led to different management guidelines for ITP worldwide, including new approaches developed in Spain.
- A study using the Delphi methodology reached an 81% consensus on managing adult ITP patients, resulting in practical recommendations, but some areas still require further clarification and improvement.
There are not many publications that provide a holistic view of the management of primary and secondary ITP as a whole, reflecting the similarities and differences between the two. Given the lack of major clinical trials, we believe that comprehensive reviews are much needed to guide the diagnosis and treatment of ITP today. Therefore, our review addresses the contemporary diagnosis and treatment of ITP in adult patients.
View Article and Find Full Text PDFRecommendations on the Management of Patients with Immune Thrombocytopenia (ITP) in the Context of SARS-CoV-2 Infection and Vaccination: Consensus Guidelines from a Spanish ITP Expert Group.
Infect Dis Ther
February 2023
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease with highly variable presentation, characteristics, and clinical course. Thrombocytopenia is a common complication of many viral infections, including SARS-CoV-2. In addition, both de novo ITP and exacerbation of ITP after vaccination against SARS-CoV-2 have been reported.
View Article and Find Full Text PDFObjectives: Diagnosis of Wilson disease (WD) is difficult and, as early detection may prevent all symptoms, it is essential to know the exact prevalence to evaluate the cost-efficacy of a screening program. As the number of WD patients was high in our population, we wished to estimate prevalence by determining the carrier frequency for clinically relevant ATP7B mutations.
Methods: To estimate prevalence, screening for the most prevalent mutation was performed in 1661 individuals with ancestry in Gran Canaria, and the frequency of other mutations was estimated from patient records.