Publications by authors named "F Farowski"
Article Synopsis
- The study focuses on the less-studied role of intestinal eukaryotes, specifically Blastocystis and Entamoeba hartmanni, in the gut health of asymptomatic individuals in Côte d'Ivoire, contrasting with previous research in symptomatic people from developed nations.
- Analysis involved amplifying specific regions of bacterial DNA to examine gut microbiota composition, revealing that individuals with both protozoa showed greater microbial diversity and different bacterial compositions than those without.
- Findings suggest that Blastocystis ST1 and ST2, when associated with E. hartmanni, may contribute positively to intestinal health, indicated by increased diversity and certain beneficial bacterial levels.
The composition of gut microbiota plays a pivotal role in priming the immune system and thus impacts autoimmune diseases. Data on the effects of gut bacteria eradication via systemic antibiotics on immune neuropathies are currently lacking. This study therefore assessed the effects of antibiotics-induced gut microbiota alterations on the severity of experimental autoimmune neuritis (EAN), a rat model of Guillain-Barré Syndrome (GBS).
View Article and Find Full Text PDFBackground: Composition of the intestinal microbiota has been correlated to therapeutic efficacy of immune checkpoint inhibitors (ICI) in various cancer entities including melanoma. Prediction of the outcome of such therapy, however, is still unavailable. This prospective, non-interventional study was conducted in order to achieve an integrated assessment of the connection between a specific intestinal microbiota profile and antitumor immune response to immune checkpoint inhibitor therapy (anti-PD-1 and/or anti-CTLA-4) in melanoma patients.
View Article and Find Full Text PDFBackground: Immune recovery following allogeneic hematopoietic stem cell transplantation (allo-HSCT) decisively influences the occurrence of opportunistic infections, one of the leading causes of death among this group of patients. Yet, today, there are no laboratory parameters mirroring immune function sufficiently. Torque teno virus (TTV) has already proven itself as a functional immune marker in other settings.
View Article and Find Full Text PDFBackground And Purpose: The gut microbiome is involved in autoimmunity. Data on its composition in chronic inflammatory demyelinating polyneuropathy (CIDP), the most common chronic autoimmune disorder of peripheral nerves, are currently lacking.
Methods: In this monocentric exploratory pilot study, stool samples were prospectively collected from 16 CIDP patients (mean age 58 ± 10 years, 25% female) before and 1 week after administration of intravenous immunoglobulin (IVIg).