Publications by authors named "F Farinha"
Background Sjögren's syndrome (SS) is a chronic systemic autoimmune disorder characterized by lymphocytic infiltration of the exocrine glands. Although primarily affecting these glands, the syndrome can also involve several organs. Interstitial lung disease is one of the most severe complications associated with SS.
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- This study focused on comparing clinical and laboratory characteristics of neuromyelitis optica spectrum disorders (NMOSD) patients with autoimmune diseases (AID) versus those without AID.
- Among the 46 NMOSD patients analyzed, 16 (34.8%) had polyautoimmunity, with most being women around 40 years old, and AID often preceded NMOSD symptoms by an average of 7 years.
- The findings indicated that NMOSD patients with polyautoimmunity had a higher recurrence of their disease and more inflammatory cerebrospinal fluid, although both groups had similar initial clinical symptoms and no significant differences in long-term functional outcomes.
Background: Stress has been linked to worsening symptoms and increased disease activity in patients with Systemic lupus erythematosus (SLE). Life-events are individual stress points, and there is conflicting evidence regarding their role in SLE activity and disease perception.
Methods: Adult SLE patients were recruited for the study.
Background: Females diagnosed with systemic lupus erythematosus (SLE) face an elevated risk of adverse pregnancy outcomes (APOs). However, the evidence regarding whether a similar association exists in patients with undifferentiated connective tissue disease (UCTD) is inconclusive.
Methods: We conducted a retrospective review (2006-2019) of pregnancy outcomes among patients with SLE (n = 51) and UCTD (n = 20) within our institution.
Article Synopsis
- The study aimed to compare proliferative (PLN) and membranous (MLN) lupus nephritis (LN) in terms of clinical presentation and long-term health outcomes, focusing on predictors for chronic kidney disease (CKD).
- A multicenter observational approach involved analyzing data from 260 patients with biopsy-confirmed PLN, MLN, and mixed LN, and used Cox regression to identify CKD predictors over an average follow-up of 8 years.
- Results indicated that MLN patients generally had better kidney function, with lower serum creatinine and more normalized complement levels, while an estimated glomerular filtration rate (eGFR) of 75 mL/min/1.73 m2 after one year was the strongest