Postoperative physical activity limitations and balance changes on patients who have been operated for breast cancer.

Objective: The purpose of this study is to assess the postoperative physical activity limitations and balance changes in patients who have been operated on for breast cancer. Some physical activity limitations and balance disorders can be expected after breast cancer surgery.

Methods: From 2008 to 2016, 112 patients who underwent breast cancer surgery were included in this study.

Is it possible to predict mortality in patients with high-grade blunt liver injury? A single trauma center study.

Background: Blunt abdominal trauma constitutes a significant portion of trauma cases and is often associated with liver injury. Given that high-grade liver injuries remain life-threatening, identifying patients who will likely require more vigilant attention and care is crucial. This study aims to determine the parameters that increase mortality in patients with high-grade liver trauma.

Blunt splenic trauma: Analysis of predictors and risk factors affecting the non-operative management failure rate.

Background: Non-operative management (NOM) has become a standard treatment in hemodynamically stable patients with blunt splenic trauma. Studies have identified numerous predictors and risk factors for NOM. However, these factors' role in NOM failure continues to be debated.

CRISPR/Cas9-mediated Bag-1 knockout increased mesenchymal characteristics of MCF-7 cells via Akt hyperactivation-mediated actin cytoskeleton remodeling.

Bag-1 protein is a crucial target in cancer to increase the survival and proliferation of cells. The Bag-1 expression is significantly upregulated in primary and metastatic cancer patients compared to normal breast tissue. Overexpression of Bag-1 decreases the efficiency of conventional chemotherapeutic drugs, whereas Bag-1 silencing enhances the apoptotic efficiency of therapeutics, mostly in hormone-positive breast cancer subtypes.