Publications by authors named "F Eyer"
Patients with recreational drug and ethanol poisoning often present with reduced consciousness, coma, or disorientation. It is often unclear if there was recent head trauma. Algorithms to perform cranial computed tomography (cCT) like the Canadian CT Head Rule (CCHR), the National Emergency X-Radiography Utilization Study Head CT Decision Instrument (NEXUS DI), or the New Orleans Criteria (NOC) exist for patients with head trauma.
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- Quetiapine has become a widely used drug in cases of acute intoxication and a literature review was conducted to understand its effects and risks.
- The study analyzed 134 cases of quetiapine ingestion, revealing a common median dose of 10 g and a peak serum concentration (c) of 4 mg/L, with a longer half-life during acute intoxication compared to therapeutic use.
- Higher doses and concentrations of quetiapine were linked to more severe clinical symptoms like central nervous system depression and tachycardia, with doses above 3 g or concentrations above 2 mg/L indicating a high risk for severe complications.
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- A study analyzed 872 patients admitted for acute recreational drug poisoning between 2014 and 2022 to evaluate discrepancies between their self-reported drug use and toxicological tests.
- The results showed that patients typically underreported the number of substances ingested, with benzodiazepines, Pregabalin, and THC being the most commonly missed drugs, while opiates and opioids were linked to severe outcomes, including cardiopulmonary failure and death.
- The findings suggest that improvements in understanding clinical management and substance use patterns are needed, as legislation changes have influenced detection rates of certain drugs over time.
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- This study evaluates the clinical features and outcomes of acute cannabis toxicity versus acute synthetic cannabinoid receptor agonist toxicity in European emergency departments from 2013-2020.
- Using data from the European Drug Emergencies Network Plus, researchers analyzed 2,657 cases of cannabis exposure and 503 cases of synthetic cannabinoid exposure to compare their effects.
- The findings indicate that synthetic cannabinoid exposures are linked to more severe neuropsychiatric symptoms, while cannabis exposures are associated with cardiovascular issues.