Skin temperature and nitric oxide in premenopausal and postmenopausal women with fibromyalgia.

Objective: This study aimed to investigate skin temperature, indicative of peripheral vascular blood flow, core body temperature and nitric oxide (NO) levels in premenopausal and postmenopausal women with fibromyalgia (FM) and controls.

Method: A case-control study was carried out in 32 healthy premenopausal and 52 healthy postmenopausal women and in 17 premenopausal and 53 postmenopausal women with FM. Hand skin temperature was measured using infrared thermography, tympanic and axillary temperature with an infrared thermometer, and serum NO levels using an ozone chemiluminescence-based method.

Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group.

In the past decade, precise targeting through genome editing has emerged as a promising alternative to traditional therapeutic approaches. Genome editing can be performed using various platforms, where programmable DNA nucleases create permanent genetic changes at specific genomic locations due to their ability to recognize precise DNA sequences. Clinical application of this technology requires the delivery of the editing reagents to transplantable cells or to tissues and organs for approaches, often representing a barrier to achieving the desired editing efficiency and safety.

Telemedicine Use and Hypertension Control in an Urban Community Health Center Cohort.

Background: Real-time or synchronous telemedicine can be a valuable adjunctive strategy for chronic disease management, but few studies have assessed its impact on hypertension control among safety-net populations.

Objective: To evaluate whether telemedicine is associated with blood pressure (BP) control.

Design: Retrospective cohort study.

Different Correlation Patterns Between Circulating Amino Acids and Body Temperature in Fibromyalgia Syndrome: A Cross-Sectional Study.

The aim of this study was to analyze the association between circulating amino acids and central and peripheral body temperature in subjects with and without fibromyalgia syndrome (FMS). A total of 47 patients with FMS and 59 healthy subjects were included in the study. The concentration of amino acids was determined in serum samples using a fluorimeter coupled with a high-performance liquid chromatography system.

Copper and Silver Trispyrazolylborate-Phosphinoazide Complexes: Synthesis, Characterization, and Nitrene Generation.

Phosphinoazide complexes of the composition TpM-L (M = Cu, Ag, and L = 2-azido-1,3-bis(2,6-diisopropylphenyl)-2,3-dihydro-1-1,3,2-diazaphosphole) have been synthesized and structurally characterized. Their thermal decomposition led to cyclodiphosphazenes as a result of the metal-mediated coupling of two nitrene units in a process that takes place in both a stoichiometric and catalytic manner. Experimental data have allowed proposing a mechanistic pathway for this new transformation.