Evaluating fatty acid profiles in anisakid nematode parasites and adjacent tissue of European hake (Merluccius merluccius): a first insight into local host-parasite lipid dynamics.

Parasitism in fish is a widespread and ecologically significant phenomenon, affecting fish in both wild and aquaculture environments. Comprehending parasitism is essential for managing fish populations, protecting fish health, and preventing human exposure to zoonotic parasites. Understanding lipid dynamics between parasitic organisms and their hosts is crucial for elucidating host-parasite interactions.

On the role of VP3-PI3P interaction in birnavirus endosomal membrane targeting.

Birnaviruses are a group of double-stranded RNA (dsRNA) viruses infecting birds, fish, and insects. Early endosomes (EE) constitute the platform for viral replication. Here, we study the mechanism of birnaviral targeting of EE membranes.

Reflexive and voluntary saccades as a proxy for bradykinesia and apathy in Parkinson's disease.

Background: Parkinson's disease (PD) encompasses motor (e.g., bradykinesia) and non-motor (e.

Investigation of Bile Salt Hydrolase Activity in Human Gut Bacteria Reveals Production of Conjugated Secondary Bile Acids.

Through biochemical transformation of host-derived bile acids (BAs), gut bacteria mediate host-microbe crosstalk and sit at the interface of nutrition, the microbiome, and disease. BAs play a crucial role in human health by facilitating the absorption of dietary lipophilic nutrients, interacting with hormone receptors to regulate host physiology, and shaping gut microbiota composition through antimicrobial activity. Bile acid deconjugation by bacterial bile salt hydrolase (BSH) has long been recognized as the first necessary BA modification required before further transformations can occur.