Feed additives for methane mitigation: A guideline to uncover the mode of action of antimethanogenic feed additives for ruminants.

This publication aims to provide guidelines of the knowledge required and the potential research to be conducted in order to understand the mode of action of antimethanogenic feed additives (AMFA). In the first part of the paper, we classify AMFA into 4 categories according to their mode of action: (1) lowering dihydrogen (H) production; (2) inhibiting methanogens; (3) promoting alternative H-incorporating pathways; and (4) oxidizing methane (CH). The second part of the paper presents questions that guide the research to identify the mode of action of an AMFA on the rumen CH production from 5 different perspectives: (1) microbiology; (2) cell and molecular biochemistry; (3) microbial ecology; (4) animal metabolism; and (5) cross-cutting aspects.

Spatial-temporal distribution of chikungunya virus in Brazil: a review on the circulating viral genotypes and () as a potential vector.

Chikungunya virus (CHIKV) is mainly transmitted by the invasive mosquito () in tropical and subtropical regions worldwide. However, genetic adaptations of the virus to the peri domestic mosquito vector () has resulted in enhanced vector competence and associated epidemics and may contribute to further geographic expansion of CHIKV. However, evidence-based data on the relative role of in CHIKV transmission dynamics are scarce, especially in regions where is the main vector, such as in Brazil.

Predictive models of injury risk in male professional football players: a systematic review.

Background: One of the challenges for professional football players is injuries. Due to their influence on their teams, injuries greatly impact the sports business. This research aims to assess predictive models of injury risk in male professional football players.

Anti-inflammatory and antinociceptive effects of LQFM275 - A new multi-target drug.

Compound (4-(3,5-di-tert-butyl-4-hydroxybenzylamine)benzenesulfonamide) (LQFM275) was designed and synthesized from darbufelone and sulfanilamide as a new multi-target for the treatment of inflammatory diseases. LQFM275 showed a great range of safe cytotoxicity profile (100-400 μM) evaluated by MTT assay, preventing damage induced by lipopolysaccharide (LPS) in EA.hy926 cell line.

Orange peel essential oil in rice starch encapsulating material for antimicrobial application against Escherichia coli.

This study investigated the formation of fibers and capsules using rice starch as a wall material to encapsulate orange peel essential oil (OPEO) by electrospinning for antimicrobial applications. Rice starch at a concentration of 20 % (w/v) and varying OPEO concentrations (30 %, 40 %, and 50 %, w/w) were used to produce materials. Free OPEO was analyzed for its chemical profile and antimicrobial activity.