Publications by authors named "F Enseleit"
Article Synopsis
- A significant number of heart failure patients progress to advanced stages, which heightens health risks, and some may qualify for advanced treatments like ventricular assist devices (VAD).
- This study assessed vascular function in 34 patients with VAD compared to 34 patients with advanced heart failure, finding that those with VAD showed improved endothelial function in larger arteries but not in microcirculation.
- The findings suggest that while VAD implantation benefits endothelial function at the arterial level, it does not enhance microvascular function in advanced heart failure patients.
The diagnostic approach to idiopathic giant-cell myocarditis (IGCM) is based on identifying various patterns of inflammatory cell infiltration and multinucleated giant cells (GCs) in histologic sections taken from endomyocardial biopsies (EMBs). The sampling error for detecting focally located GCs by histopathology is high, however. The aim of this study was to demonstrate the feasibility of gene profiling as a new diagnostic method in clinical practice, namely in a large cohort of patients suffering from acute cardiac decompensation.
View Article and Find Full Text PDFBackground: Polymerase chain reaction analyses of cardiac tissues have detected viral sequences in up to 67% of cases of myocarditis. However, viruses have not been implicated in giant cell myocarditis (GCM). Furthermore, efforts to detect viruses implicated in myocarditis have been unsuccessful in more accessible samples such as peripheral blood.
View Article and Find Full Text PDFObjectives: We aimed to assess the diagnostic performance of a combined protocol with coronary computed tomography angiography (CCTA) and stress CT perfusion imaging (CTP) in heart transplant patients for comprehensive morphological and functional imaging.
Methods: In this prospective study, 13 patients undergoing routine follow-up 8±6 years after heart transplantation underwent CCTA and dynamic adenosine stress CTP using a third-generation dual-source CT scanner, cardiac magnetic resonance (MR) adenosine stress perfusion imaging at 1.5 T, and catheter coronary angiography.
Aims: Retinal vessel analysis (RVA) represents a novel, non-invasive, and reliable method to study the microcirculation in the eye. The goal of this study was to assess the extent of retinal microvascular dysfunction in patients with chronic heart failure (CHF) compared to controls and established measures of vascular function.
Methods And Results: In this prospective, single-centre, observational study, 74 patients with compensated CHF (mean age 63.