The role of delta phase for temporal predictions investigated with bilateral parietal tACS.

Background: Previous research has shown that temporal prediction processes are associated with phase resets of low-frequency delta oscillations in a network of parietal, sensory and frontal areas during non-rhythmic sensory stimulation. Transcranial alternating current stimulation (tACS) modulates perceptually relevant brain oscillations in a frequency and phase-specific manner, allowing the assessment of their functional qualities in certain cognitive functions like temporal prediction.

Objective: We addressed the relation between oscillatory activity and temporal prediction by using tACS to manipulate brain activity in a sinusoidal manner.

Synthesis and Structural Characterization of -Carboranylamidine Derivatives.

In this contribution, the first amidinate and amidine derivatives of -carborane are described. Double lithiation of -carborane () with -butyllithium followed by treatment with 1,3-diorganocarbodiimides, R-N=C=N-R (R = Pr, Cy (= cyclohexyl)), in DME or THF afforded the new -carboranylamidinate salts -CHB[C(NPr)Li(DME)] () and -CHB[C(NCy)Li(THF)] (). Subsequent treatment of and with 2 equiv.

Synthesis and Structure of Alkaline Earth Bis{hydrido-tris(3,5-diisopropyl-pyrazol-1-yl)borate} Complexes: Ae(Tp) (Ae = Mg, Ca, Sr, Ba).

The synthesis and structural characterization of Ae(Tp) (Ae = Mg, Ca, Sr, Ba; Tp = hydrido-tris(3,5-diisopropyl-pyrazol-1-yl)borate) are reported. In the crystalline state, the alkaline earth metal centers are six-coordinate, even the small Mg ion, with two κ-,',''-Tp ligands, disposed in a bent arrangement (B···Ae···B < 180°). However, contrary to the analogous Ln(Tp) (Ln = Sm, Eu, Tm, Yb) compounds, which all exhibit a bent-metallocene structure close to symmetry, the Ae(Tp) compounds exhibit a greater structural variation.

Genetic determinants of fitness during biofilm growth.

is an environmental bacterium and an opportunistic human pathogen. It is also a well-established model organism to study bacterial adaptation to stressful conditions, such as those encountered during an infection process in the human host. Advancing knowledge on adaptation to biofilm growth conditions is bound to reveal novel strategies and targets for the treatment of chronic biofilm-associated infections.

Organism-specific depletion of highly abundant RNA species from bacterial total RNA.

High-throughput sequencing has become a standard tool for transcriptome analysis. The depletion of overrepresented RNA species from sequencing libraries plays a key role in establishing potent and cost-efficient RNA-seq routines. Commercially available kits are known to obtain good results for the reduction of ribosomal RNA (rRNA).