Publications by authors named "F El Otmani"
Objective: To develop the Still's Disease Activity Score (SDAS).
Methods: We used data from the prospective adult-onset Still's disease cohort study and evaluated the disease activity. An expert group selected the most frequent, reproducible, and objective variables significantly modified in statistical analysis when comparing patients in the active group and in the remission group.
Article Synopsis
- A study in Morocco analyzed 134 Pseudomonas aeruginosa (Pa) isolates, revealing that 18 were resistant to carbapenems, critical antibiotics for treating severe infections.
- Advanced testing methods confirmed the resistance and identified specific genes responsible for this problem, highlighting a worrying trend of multidrug resistance among these pathogens.
- The findings underscore the urgent need for careful antibiotic selection and monitoring, as most isolates exhibited extensive drug resistance, though some remained susceptible to colistin and cefiderocol.
Introduction: In the last decade, an immuno-modulatory effect of vitamin D supplementation have emerged as a potential therapeutic approach for some inflammatory and autoimmune diseases. As previously reported, vitamin D deficiency was strongly linked to several diseases as Behçet's disease (BD). BD is a chronic systemic inflammatory disorder with autoimmunity, genetic and environmental factors involvement.
View Article and Find Full Text PDFObjective: This study was performed to develop a new diagnostic algorithm for adult-onset Still's disease (AOSD).
Methods: We conducted a multicenter prospective nationwide case-control study in tertiary Internal Medicine, Rheumatology, and Infectious Diseases departments, to include successively patients with suspected AOSD based on the presence of two or more major criteria of Yamaguchi and/or Fautrel classifications. Patients were classified as AOSD or controls according to a predefined procedure.