Publications by authors named "F Ebert"

Copper (Cu) is an essential trace element involved in fundamental physiological processes in the human body. Even slight disturbances in the physiological Cu homeostasis are associated with the manifestation of neurodegenerative diseases. While suggesting a crucial role of Cu in the pathogenesis, the exact mechanisms of Cu neurotoxicity involved in the onset and progression of neurological diseases are far from understood.

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The blood-brain barrier (BBB) serves as a crucial interface, regulating the transfer of trace elements (TEs) such as copper (Cu) and zinc (Zn) between the bloodstream and the brain. Cu and Zn are essential for maintaining neural function and enzymatic processes. Understanding the interplay of Cu and Zn with the BBB is crucial for elucidating their roles in neurological health and disease.

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  • Posttraumatic osteoarthritis often leads to total knee arthroplasty (TKA), and this study investigates how a history of patella fractures affects postoperative complications.
  • Researchers examined TKA patients with prior patella fractures and compared them to a control group using data from a national database, focusing on complications within 90 days and healthcare costs.
  • Results revealed that those with a history of patella fractures had lower pulmonary embolism rates but higher risks for infections, revision surgeries, and increased healthcare costs, indicating the need for better patient risk assessment.
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  • - An on-chip asymmetric directional coupler (DC) is crucial for converting fundamental modes into higher-order modes in mode-division multiplexing (MDM) technology.
  • - The study introduces a method using silicon ion implantation to adjust the effective refractive index of waveguides, achieving significant transmission changes up to 18 dB with just one implantation step.
  • - This innovative tuning technique allows for greater control over mode transmission and may enhance the efficiency and effectiveness of mode converters in integrated photonic systems, potentially benefiting emerging photonic neuromorphic computing applications.
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From organs to subcellular organelles, trace element (TE) homeostasis is fundamental for many physiological processes. While often overlooked in early stages, manifested TE disbalance can have severe health consequences, particularly in the context of aging or pathological conditions. Monitoring TE concentrations at the mitochondrial level could identify organelle-specific imbalances, contributing to targeted diagnostics and a healthier aging process.

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