Publications by authors named "F E Munro"
Background: The coronavirus (COVID-19) pandemic affected the presentation of many conditions. This study analyses and describes the impact of the COVID-19 pandemic on the management of appendicitis in children and the role of laparoscopy.
Materials And Methods: We performed a prospective (during the pandemic) and retrospective (historic control) review of the management of appendicitis in a tertiary paediatric surgical unit.
Article Synopsis
- * Current CTC isolation methods, like CellSearch, have limitations including cost and reliance on a single marker, which leads to challenges in both detection and monitoring of cancer.
- * The MetaCell method offers a novel approach by using size differences to filter CTCs from blood, allowing for easier enrichment and subsequent analysis through immunohistochemical staining.
Genomic analysis of tumors is transforming our understanding of cancer. However, although a great deal of attention is paid to the accuracy of the cancer genomic data itself, less attention has been paid to the accuracy of the associated clinical information that renders the genomic data useful for research. In this brief communication, we suggest that omissions and errors in clinical annotations have a major impact on the interpretation of cancer genomic data.
View Article and Find Full Text PDFCirculating tumour cells (CTC) from solid tumours are a prerequisite for metastasis. Isolating CTCs and understanding their biology is essential for developing new clinical tests and precision oncology. Currently, CellSearch is the only FDA (U.
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