Publications by authors named "F E Diehn"
Background And Purpose: Studies show a modest yield for image-guided biopsy of suspected vertebral osteomyelitis-discitis. Many studies evaluate factors to improve diagnostic yield, and few studies assess how biopsy results impact clinical management. We aim to evaluate the impact of biopsy results on clinical management in suspected vertebral osteomyelitis-discitis.
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- - Identifying bacteria in native vertebral osteomyelitis is difficult due to slow culture methods and varying accuracy of molecular diagnostics like 16S PCR and metagenomic sequencing, creating uncertainty in their clinical effectiveness.
- - A study conducted in 2023 reviewed data from January 1970 to June 2023 to evaluate the sensitivity, specificity, and diagnostic odds ratios of these molecular methods in adults suspected of having this condition, excluding certain types of osteomyelitis.
- - Out of 3403 studies reviewed, 10 were selected for analysis based on strict criteria, ultimately involving 391 patients, revealing moderate risk of bias but good applicability for diagnosing native vertebral osteomyelitis.
Background: SynthesiZed Improved Resolution and Concurrent nOise reductioN (ZIRCON) is a multi-kernel synthesis method that creates a single series of thin-slice computed tomography (CT) images displaying low noise and high spatial resolution, increasing reader efficiency and minimizing partial volume averaging.
Purpose: To compare the diagnostic performance of a single set of ZIRCON images to two routine clinical image series using conventional CT head and bone reconstruction kernels for diagnosing intracranial findings and fractures in patients with trauma or suspected acute neurologic deficit.
Material And Methods: In total, 50 patients underwent clinically indicated head CT in the ER (15 normal, 35 abnormal cases).
Background: Diagnostic methods for native vertebral osteomyelitis (NVO) often yield inconclusive results. Image-guided spine biopsies for culture are specific but diagnose NVO in only 50% of cases. Pre-exposure to antimicrobials further reduces diagnostic yield.
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- Native Vertebral Osteomyelitis (NVO) is becoming more common, but doctors still struggle to treat it effectively, leading to many patients relapsing or having other health issues later on.
- The study aimed to collect and compare how different sources define NVO and analyze the details in their definitions.
- They found 92 different ways people defined NVO in 171 studies, realizing that most definitions focused on combining symptoms, medical imaging, and lab tests.