Publications by authors named "F E Awadallah"

Article Synopsis
  • Sulfonamide acridine derivatives show a variety of biological activities and were synthesized to test their effectiveness against cancer cells.
  • Eleven compounds were evaluated for their ability to inhibit cell growth, induce apoptosis, and affect cell cycle dynamics in three different cancer cell lines, along with their interactions with topoisomerase enzymes.
  • One compound emerged as the most effective, demonstrating potent anticancer properties and significant inhibition of the Topo I and II enzymes, indicating its potential for development as an anticancer drug.
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Silver nanoparticles-loaded hydrogel nanocomposites are exploited for medicinal and pharmaceutical applications. Hydrogel nanocomposites were prepared from acrylamide (Am), chitosan (CS) and AgNO utilizing gamma rays. Diverse variables were applied in preparation of silver nanoparticles-laoded hydrogel nanocomposites of (PAm/CS)-AgNPs such as influence of radiation dose and influnece of CS concentration.

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Sulfonamides have gained prominence as versatile agents in cancer therapy, effectively targeting a spectrum of cancer-associated enzymes. This review provides an extensive exploration of their multifaceted roles in cancer biology. Sulfonamides exhibit adaptability by acting as tyrosine kinase inhibitors, disrupting pivotal signaling pathways in cancer progression.

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The oxidation of Carbon monoxide (CO) to Carbon dioxide (CO) is one of the most extensively investigated reactions in the field of heterogeneous catalysis, and it occurs via molecular rearrangements induced by catalytic metal atoms with oxygen intermediates. CO oxidation and CO capture are instrumental processes in the reduction of green-house gas emissions, both of which are used in low-temperature CO oxidation in the catalytic converters of vehicles. CO oxidation and CO adsorption at different temperatures are evaluated for palladium-supported silica aerogel (Pd/SiO).

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