Publications by authors named "F Donders"
Currently, the rising prevalence of resistant species, particularly , as well as non-albicans isolates such as and , represent challenges in their management. In this review, we aimed to explore the current management of fluconazole-resistant vulvovaginal candidiasis (FRVVC). Identified studies focused on alternative antifungal therapies, including boric acid, nystatin, and newer agents like oteseconazole and ibrexafungerp.
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- - Vulvovaginal candidosis (VVC) is a prevalent condition among women, but existing diagnostic methods are often inefficient and result in delayed treatment due to the need for specialized training and lengthy processes.
- - A review of 23 studies showed that molecular diagnostic tools, particularly NAAT/PCR assays, have high sensitivity and specificity for VVC compared to traditional methods, while simpler DNA probes have lower sensitivity.
- - Despite the advancements in molecular diagnostics, traditional methods still play an important role, especially in settings with limited resources, and emerging technologies like AI show potential to further enhance diagnosis and treatment outcomes.
Objective: To evaluate the effect of hormonal suppression of endometriosis on the size of endometriotic ovarian cysts.
Data Sources: The authors searched MEDLINE, PubMed, Cochrane Central Register of Controlled Trials, Embase, and ClinicalTrials.gov from January 2012 to December 2022.
Article Synopsis
- The study investigates the short- and long-term impacts of SARS-CoV-2 on sperm quality, revealing a lack of established knowledge due to insufficient longitudinal research.
- Evaluating sperm parameters included assessments like motility, morphology, DNA damage, and the presence of anti-sperm antibodies, which classified patients based on their antibody response post-infection.
- Findings indicate that SARS-CoV-2 affects various sperm quality metrics, with most changes being temporal and suggesting that individual immune response levels influence recovery to baseline sperm quality after infection.
New developments in the management of vulvovaginal atrophy: a comprehensive overview.
Expert Opin Pharmacother
April 2023
Introduction: Proper recognition and individualized therapy of vulvovaginal atrophy (VVA) is paramount.
Areas Covered: Assessment of VVA should be performed using several questionnaires in combination with wet mount microscopy to determine Vaginal Cell Maturation Index (VCMI) and infections. PubMed searches were carried out between 1 march 2022 and 15 October 2022.