Publications by authors named "F Dogu Geyik"
Acute lower limb ischemia caused by repeat deployment of vascular closure device.
J Vasc Access
September 2024
Vascular closure devices are used to facilitate faster hemostasis and earlier ambulation, improve patient comfort, and reduce length of hospital stay after percutaneous endovascular procedures. However, their use may rarely be associated with limb ischemia due to endothelial damage and arterial thrombosis. This report illustrates the case of a patient who experienced acute lower limb ischemia due to superficial femoral artery occlusion caused by repeat closure with Angio-Seal vascular closure device within 30 days in a small-caliber superficial femoral artery.
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- The study investigates the effects of two anaesthetic agents, sevoflurane and desflurane, on the endothelial glycocalyx during laparoscopic hysterectomy by measuring levels of syndecan-1 and heparan sulfate.
- Results show no significant difference in glycocalyx markers between the two anaesthetics at any time point, but there was a notable change in heparan sulfate levels within the desflurane group.
- The conclusion indicates that both anaesthetics can mitigate surgical stress on the endothelial glycocalyx, with desflurane offering a more substantial protective effect than sevoflurane.
Nanofibers have high potential through their high porosity, small pore sizes, lightweight materials, and their ability to mimic the extracellular matrix structure for use in the manufacture of wound dressings for wound treatment. In this study, poly(lactic--glycolic acid) (PLGA) nanofibers were produced by electrospinning. Propolis was loaded into the PLGA nanofibers by the dropping method.
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- The study focused on identifying (epi)genetic factors in children born small for gestational age (SGA) experiencing undiagnosed syndromic short stature, involving 29 selected cases from a syndromic SGA cohort.
- Advanced genetic analysis techniques like chromosomal microarray and whole exome sequencing were used, leading to the detection of pathogenic variants and uniparental disomy in several patients.
- The findings revealed a 55.2% diagnosis rate, introduced 15 rare syndromes linked to SGA, and identified novel genes and copy number variants (CNVs), highlighting the complexity and diversity of syndromic short stature.
Background: Osteogenesis imperfecta (OI) is a heterogeneous group of inherited disorders characterised by susceptibility to fractures, primarily due to defects in type 1 collagen. The aim of this study is to present a novel OI phenotype and its causative candidate gene.
Methods: Whole-exome sequencing and clinical evaluation were performed in five patients from two unrelated families.