The functional limitation of patients with obliterative arterial disease, and with intermittent claudication, damages their quality of life. The purpose of this trial was to compare the effects of nicergoline and naftidrofuryl on the quality of life and the functional discomfort of the 131 patients with claudication. It was a multicentre, randomised, double-blind trial with parallel groups.
View Article and Find Full Text PDFAmong the numerous risk factors for atherosclerosis, 2 are particularly important: hypertension and primary or secondary abnormalities of plasma lipids and lipoproteins. Antihypertensive treatments significantly decrease the risk of cerebrovascular accidents, renal failure or hypertensive cardiomyopathy, but they have little influence on coronary artery disease. It has been suggested that some antihypertensive agents may have deleterious effects by altering serum lipoproteins and this may override the benefit of blood pressure reduction.
View Article and Find Full Text PDFAnn Otolaryngol Chir Cervicofac
June 1990
We report the case of a 54 years old man suffering with chronic otorrhea. The surgical procedure let us be surprised at a non specific cyst located in the "additus ad antrum", close to the incus but no damaging it. The result of the histologic examination was: Malherbe's calcifying cyst.
View Article and Find Full Text PDFCicletanine, an antihypertensive drug heralding a new pharmacological family, was tested in a short-term open trial on 39 hypertensive patients with normal or increased lipidemia according to the W.H.O.
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