Publications by authors named "F Dies"

The efficacy in restoring a buccal dehiscence after tooth extraction has been studied in 12 consecutive cases using guided bone regeneration with (6 patients) or without (6 patients) a biomaterial (DFDBA or Bio Oss) beneath an e-PTFE membrane. A correlation between the clinical impression of density at drilling time and the histological signs of bone formation has been evaluated too. The membrane was removed after 6 or 9 months and a biopsy was performed.

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Article Synopsis
  • Xanomeline tartrate is a drug that specifically targets the M1 receptor and has shown good tolerance at doses up to 50 mg in healthy elderly people.
  • A study involving 48 Alzheimer's patients tested eight different doses of xanomeline tartrate over a week to find the maximum tolerated dose (MTD).
  • The study found that the MTD for Alzheimer's patients was 100 mg taken three times a day, which is twice as high as the MTD established in healthy elderly volunteers.
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Lactate uptake (Qlact) and oxidation (QCO2lact), oxygen consumption (QO2) and net tubular Na+ reabsorption (TNa), were estimated in pentobarbital-anesthetized dogs under control conditions and following unilateral intrarenal injection of ouabain or intravenous infusion of acetazolamide, ethacrynic acid, or furosemide. QCO2lact accounted for approximately half of simultaneous Qlact and for about one-third of QO2 in control periods. Ouabain injection resulted in significant decreases in several functions of the injected kidney: TNa, 46%; TNa/FNa, 36%; QO2, 40%; Qlact, 59%; and QCO2lact, 70%.

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