Publications by authors named "F Di Candia"
Aims: New technology has been reported as a factor driving people to choose an automatic insulin delivery system (AIDs) and to sustain its acceptance. We aimed to explore the role of continuous glucose monitoring (CGM) technology (instant scanning vs. real-time) and insulin treatment modality to determine the future acceptance of AIDs among T1D individuals.
View Article and Find Full Text PDFBackground: Umbilical venous catheters (UVCs) are the standard of care in neonatal intensive care units (NICUs) to administer fluids, parenteral nutrition and medications, although complications may occur, including central line-associated blood stream infections (CLABSIs). However, the dwell time to reduce CLABSI risk remains an open issue.
Methods: We performed a single-center retrospective study of newborns hospitalized in the Modena NICU with at least one UVC inserted over a 6-year period (period 1: January 2011-December 2013; period 2: January 2019-December 2021).
Article Synopsis
- The study aimed to create a questionnaire that evaluates how likely individuals with type 1 diabetes (T1D) are to accept Automatic Insulin Delivery systems (AIDs), focusing on their usefulness, ease of use, and trust in the technology.
- A comprehensive questionnaire was developed using a 5-point Likert scale and completed by 239 participants, including children and their parents, demonstrating excellent reliability and agreement in their responses about AIDs.
- The results showed a positive acceptance level of AIDs among both youths and parents, with parents generally recognizing more benefits, indicating the tool could be useful for clinicians and researchers in assessing the acceptance of these insulin delivery systems.
Context: The pathophysiological mechanisms underlying the natural history of glucose intolerance and its fluctuations in subjects with cystic fibrosis (CF) are still unclear.
Objective: To investigate the relationship between longitudinal changes in glucose tolerance and concomitant changes in the main parameters of insulin secretion/metabolism/action determining glucose regulation in CF subjects.
Methods: Insulin sensitivity and glucose-stimulated insulin secretion (GSIS, a biomarker of beta cell functional mass), as estimated by the Oral Glucose Sensitivity Index (OGIS) and by a sophisticated mathematical model, respectively, and insulin clearance were assessed in 127 CF subjects, aged 10-25 years, who underwent two OGTT tests over at least 1-year follow-up period.