Publications by authors named "F De Pisa"
This work aimed to improve some steps of the existing guidelines of the European Standards to obtain an Aspergillus brasiliensis ATCC 16404 spore suspension with >75% spiny spores without mycelia and a concentration of at least 1.5 × 108 CFU ml-1. Several manufacturers' combinations of "strain/medium" were assessed in terms of yield of spiny spores.
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- This study investigated the impact of mitochondrial DNA (mtDNA) levels on aggressive traits in breast cancer cells, specifically using MCF7 (ER+) and MDA-MB-231 (ER-) cell lines.
- Researchers created mtDNA-high and mtDNA-low sub-populations and found that mtDNA-high cells showed increased mitochondrial functions, higher proliferation rates, stemness features, and drug resistance.
- In vivo experiments with MDA-MB-231 cells treated with an mtDNA synthesis inhibitor, Alovudine, demonstrated a significant reduction in metastasis formation while minimally affecting tumor growth.
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- The study evaluates how knee flexion affects the femoropopliteal artery in patients with popliteal aneurysms, before and after endovascular treatment.
- Nine patients underwent CT scans in both knee flexed and extended positions to assess changes in the artery's diameter, length, and tortuosity.
- Results show significant arterial shortening and increased tortuosity post-treatment, indicating that knee movement alters arterial structure, even after stent placement.
Reactive intermediate deaminase A (RidA) is a highly conserved enzyme that catalyzes the hydrolysis of 2-imino acids to the corresponding 2-keto acids and ammonia. RidA thus prevents the accumulation of such potentially harmful compounds in the cell, as exemplified by its role in the degradation of 2-aminoacrylate, formed during the metabolism of cysteine and serine, catalyzing the conversion of its stable 2-iminopyruvate tautomer into pyruvate. Capra hircus (goat) RidA (RidA) was the first mammalian RidA to be isolated and described.
View Article and Find Full Text PDFBackground: The aim of the study is to compare the short-term and medium-term outcomes in patients who underwent open repair (OR) or endovascular repair (ER) for peripheral arterial disease (PAD) also including stratifications based on severity and year of the first intervention.
Methods: We conducted an observational retrospective single-center cohort study. We evaluated patients with PAD that primarily underwent ER, OR, minor, and major amputations in a single center from 2005 to 2020.