Publications by authors named "F De Martini"

Ustekinumab (UST) is an interleukin-12/interleukin-23 receptor antagonist approved for the treatment of Crohn's disease (CD). Only limited real-life data on the long-term outcomes of CD patients treated with UST are available. This study assessed UST's long-term effectiveness and safety in a large population-based cohort of moderate to severe CD patients.

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  • Chordomas are rare, slow-growing cancers that often occur in the lower spine area and require surgical removal, which can leave significant defects.
  • Traditional reconstruction methods often use musculocutaneous flaps, leading to higher complications at the donor site; hence, there is a need for better techniques that reduce these issues.
  • This case report introduces a new reconstruction method using gluteus maximus muscle advancement and superior gluteal artery perforator flaps for a patient after chordoma removal, resulting in successful recovery and minimal complications at the donor site during follow-up.
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  • * Researchers engineered N. oceanica using a specific strain (LP-tdTomato) to enhance ketocarotenoid production by introducing a key enzyme (CrBKT) from another alga, resulting in significant increases in carotenoid levels and a noticeable orange/red coloration in the cultures.
  • * Optimal production of canthaxanthin and ketocarotenoids was achieved at lower light intensity (150 µmol m s),
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