Publications by authors named "F D H Wilke"

Article Synopsis
  • The diagnosis of myocarditis is difficult due to varied symptoms, but magnetocardiography (MCG) shows promise for detecting it, as demonstrated in a case study of a female-to-male (FtM) patient.
  • The 38-year-old patient developed chest pain after undergoing testosterone therapy following sexual reassignment surgery, with tests revealing reduced heart function and elevated cardiac biomarkers, but no coronary artery disease.
  • The study suggests that testosterone may increase the risk of myocarditis in FtM individuals and highlights the effectiveness of MCG in diagnosing heart conditions.
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Automatic dense 3D surface registration is a powerful technique for comprehensive 3D shape analysis that has found a successful application in human craniofacial morphology research, particularly within the mandibular and cranial vault regions. However, a notable gap exists when exploring the frontal aspect of the human skull, largely due to the intricate and unique nature of its cranial anatomy. To better examine this region, this study introduces a simplified single-surface craniofacial bone mask comprising of 6707 quasi-landmarks, which can aid in the classification and quantification of variation over human facial bone surfaces.

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Automatic dense 3D surface registration is a powerful technique for comprehensive 3D shape analysis that has found a successful application in human craniofacial morphology research, particularly within the mandibular and cranial vault regions. However, a notable gap exists when exploring the frontal aspect of the human skull, largely due to the intricate and unique nature of its cranial anatomy. To better examine this region, this study introduces a simplified single-surface craniofacial bone mask comprising 9,999 quasi-landmarks, which can aid in the classification and quantification of variation over human facial bone surfaces.

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Resistance to chemotherapy is ultimately responsible for the majority of AML-related deaths, making the identification of resistance pathways a high priority. Transcriptomics approaches can be used to identify genes regulated at the level of transcription or mRNA stability but miss microRNA-mediated changes in translation, which are known to play a role in chemo-resistance. To address this, we compared miRNA profiles in paired chemo-sensitive and chemo-resistant subclones of HL60 cells and used a bioinformatics approach to predict affected pathways.

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