Publications by authors named "F Coury-Lucas"
Objective: To examine the course of interstitial lung disease associated with rheumatoid arthritis (RA-ILD) in France on treatment with Janus kinase inhibitors (JAKis) using the MAJIK-SFR registry.
Methods: Prospective national multicentre observational study identifying patients with RA-ILD from the MAJIK-SFR registry. Pulmonary assessment data were collected at JAKi initiation and follow-up visits (6 months, 12 months and a median of 21 months postinclusion), including chest high-resolution CT (HRCT), pulmonary function tests (forced vital capacity (FVC) and diffusing capacity of the lungs for carbon monoxide (DLCO)), acute exacerbations of ILD, respiratory infections and lung cancers.
Article Synopsis
- Patients with X linked agammaglobulinemia and those receiving anti-CD20 monoclonal antibodies (mAbs) for immune-mediated inflammatory diseases (IMIDs) are at increased risk for severe enterovirus (EV) infections, particularly meningoencephalitis.
- A study collected data from nine original cases and 17 previously published cases, revealing a high occurrence of meningoencephalitis (81%) and a mortality rate of 27% among affected patients treated with multiple anti-CD20 mAbs.
- The findings suggest that clinicians should consider EV infections in IMID patients presenting unusual symptoms and recognize that anti-CD20 mAbs can impair B-cell responses to EV infections, potentially indicating
Vitamin D and FGF23 play a major role in calcium/phosphate balance. Vitamin D may control bone resorption but the potential role of FGF23 has never been evaluated. The objective of this study was therefore to compare the effects of vitamin D and FGF23 on osteoclast differentiation and activity in human monocyte-derived osteoclasts.
View Article and Find Full Text PDFObjective: To evaluate the validity of using the conventional anteroposterior (AP) radiograph of the knee in order to identify joint space narrowing (JSN) at an early stage of osteoarthritis (OA).
Methods: Grading of JSN using a 0-5 score and quantitative measurement of joint space width (JSW) of the medial and lateral compartments of the tibiofemoral joint in AP and fluoroscopically assisted posteroanterior Lyon schuss (LS) radiographs of 202 patients with knee OA.
Results: Knees without definite JSN (score <2) were twice as common in AP than in LS radiographs (36.