[The diabetic foot. The Croatian model--national consensus (clinical recommendations for diagnosis, prevention and therapy)].

Diabetic foot occurs due to the loss of protective sense and circulation disorder and a marked proneness to infections. Mechanical stress of bone growths frequently leads to ulcerations. The prevention and timely treatment of diabetic foot requires the participation of both patients and all health care levels.

[Treatment of hemodynamic disorders of the peripheral arteries in a diabetic].

The experiences of the authors in treatment of disturbed haemodynamics in peripheral arteries in diabetics, as well as their complications have been here presented. The increased frequency of these disturbances, as well as pathologic changes on the parts of lower extremities in diabetics, regarding prolonged age and always better detection in new cases of diabetes have been presented in the introduction. Etiopathogenic causes and clinical picture and symptomatology of the mentioned cases are briefly described.

Effect on platelet adhesiveness in diabetics after long-term treatment with a new oral hypoglycaemic agent, gliclazide.

Gliclazide is an oral hypoglycaemic agent which has been shown in animal models to reduce platelet adhesiveness. In this study, 50 patients with maturity onset diabetes treated with gliclazide (80 mg/day) were followed up for 6 months to 1 year to assess the effect on platelet adhesiveness and control of blood sugar. A significant fall in mean platelet adhesiveness from 29% before treatment to 19.