Publications by authors named "F Cirignotta"

Perinatal depression (PND) is a common complication of pregnancy associated with serious health consequences for both mothers and their babies. Identifying risk factors for PND is key to early detect women at increased risk of developing this condition. We applied a machine learning (ML) approach to data from a multicenter cohort study on sleep and mood changes during the perinatal period ("Life-ON") to derive models for PND risk prediction in a cross-validation setting.

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This study aimed to assess the concordance of various psychometric scales in detecting Perinatal Depression (PND) risk and diagnosis. A cohort of 432 women was assessed at 10-15th and 23-25th gestational weeks, 33-40 days and 180-195 days after delivery using the Edinburgh Postnatal Depression Scale (EPDS), Visual Analogue Scale (VAS), Hamilton Depression Rating Scale (HDRS), Montgomery-Åsberg Depression Rating Scale (MADRS), and Mini International Neuropsychiatric Interview (MINI). Spearman's rank correlation coefficient was used to assess agreement across instruments, and multivariable classification models were developed to predict the values of a binary scale using the other scales.

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Article Synopsis
  • The Life-ON study aimed to assess sleep quality and disorders among pregnant women and postpartum over time, involving 439 participants from local gynecological departments.
  • Results showed that sleep quality worsened throughout pregnancy, with 34% experiencing poor sleep in the first trimester, rising to 71% in the first month postpartum; insomnia and excessive daytime sleepiness trends were also noted.
  • The study highlights the high prevalence of sleep disorders during pregnancy and postpartum, stressing the need for routine assessments to enhance early detection and management.
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Article Synopsis
  • Perinatal depression (PND) is a serious issue during pregnancy, and this study investigates whether a woman's chronotype (her natural sleep-wake cycle) could predict PND symptoms.
  • Researchers followed 299 women from early pregnancy to six months postpartum, assessing their chronotype and mood over time using various depression rating scales.
  • Results showed that evening chronotypes faced a higher risk of PND symptoms shortly after giving birth, coupled with less healthy lifestyles and more complications during pregnancy, indicating the need to evaluate chronotype in pregnant women to identify those at risk for PND.
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Objective: Perinatal depression (PND) is a severe complication of pregnancy, affecting both mothers and newborns. Bright light therapy (BLT) has only been tested in a few studies for treating either antenatal or postnatal depression. We conducted a pilot trial to investigate the efficacy and safety of BLT for PND occurring at any time across the perinatal period.

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