Publications by authors named "F Cilli"
Background: The increasing prevalence of carbapenem-resistant Enterobacteriaceae (CRE) infections among children represents a significant global concern, leading to elevated mortality rates. The aim of this study was to evaluate the risk factors, outcomes, 30-day mortality rates and contributing factors in children with CRE bloodstream infections (CRE-BSIs).
Methods: Data regarding demographic characteristics, treatment approaches and outcomes of hospitalized children aged 0-18 years diagnosed with CRE-BSIs between January 2018 and December 2022 were extracted from medical records.
Background: Intensive care unit (ICU) survival of cancer patients has improved. Urgent chemotherapy has become feasible in critically ill patients with specific organ dysfunction due to hematological malignancies.
Objective: The aim of the study was to assess ICU mortality rates and the factors associated with mortality in patients with hematologic malignancies receiving urgent chemotherapy in the ICU.
Introduction: This study reports the results of surgical anatomic reconstruction of torn coracoclavicular ligaments with an autogenous semitendinosus graft and temporary Kirschner wires (K-wires) in chronic acromioclavicular (AC) joint dislocations.
Materials And Methods: Nineteen shoulders underwent surgical anatomic reconstruction of torn coracoclavicular (CC) ligaments with an autogenous semitendinosus tendon graft and temporary K-wires for Rockwood grade III, IV and V chronic AC joint dislocations. Pre-operative data included patients' demographic characteristics, injury characteristics and surgical histories.
Article Synopsis
- The study focuses on the challenges of treating cerebrospinal fluid (CSF) shunt infections in children, particularly those caused by gram-negative bacteria and the rise of carbapenem-resistant (CR) strains.
- It analyzed 64 infection episodes among 50 pediatric patients over a 10-year period, revealing that the majority were related to CSF shunt infections, with specific bacteria like Pseudomonas and E. coli being the most common culprits.
- The research identified risk factors for CR infections, such as prior carbapenem use and extended hospital stays, and found a concerning 30-day mortality rate that was notably higher in the CR group compared to non-CR patients.
Impact of the empirical therapy timing on the clinical progress of septic shock patients.
Diagn Microbiol Infect Dis
March 2024
Article Synopsis
- The study evaluated how the timing of antimicrobial therapy impacts the clinical progress of septic shock patients, involving 204 adults diagnosed using Sepsis-3 criteria.
- Only 26.4% of patients received antibiotic treatment within the first hour after vasopressors, and there was no significant difference in one-month mortality between those with or without appropriate initial antibiotic coverage.
- Key factors influencing one-month survival included timely antibiotic initiation, patient location, and specific clinical scores, leading to a recommendation for improved training and electronic alerts for septic shock recognition and treatment in hospitals.