Immobilization-dependent bone collagen breakdown appears to increase with time: evidence for a lack of new bone equilibrium in response to reduced load during prolonged bed rest.

The purpose of this study was to evaluate the effect of prolonged immobilization on bone, in order to investigate how skeletal turnover adapts to bed rest. We examined indices of bone formation and bone resorption in the serum and urine of fifty-four patients (26 males and 28 females) immobilized after an episode of paralytic stroke. The length of immobilization ranged from 30 to 180 days.

[The efficacy of protirelin in subjects with stabilized outcomes of stroke].

Protirelin is a valid means in the therapy of patients with stabilized outcomes by stroke. It has proved efficacious in the improving of the neurologic and cognitive deficits, of conscience, alertness, mood and behaviour alterations. Furthermore in conjunction with the kinesitherapeutic treatment, protirelin has granted a general recovery of not only mental but also sphincteral conditions, of outer and inner mobility and social activities.

Determination of the spectrum of antibiotic resistance of the "Bacillus subtilis" strains of Enterogermina.

Resistance to the antibiotics most widely used in chemotherapy of the "Bacillus subtilis" strains constituting the specialty Enterogermina was measured by the method of diffusion on agar plates. The results obtained demonstrate that the mutations to resistance present in such strains confer a broad spectrum of resistance to the most important classes of antibiotics. We were also able to demonstrate a considerable number of antibiotic resistances which had not been previously recognized.