Publications by authors named "F Chirillo"
Outcome data on the use of cangrelor in older patients is limited. This post-hoc analysis of the ARCANGELO study aims to assess bleeding and ischemic outcomes with the transition from cangrelor to any oral P2Y inhibitors in age-stratified subgroups (≥75 years - older, <75 years - younger) of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Out of 995 patients, 215 (21.
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- - The study aimed to assess how the presence of raphe (a type of anatomical feature) in patients with bicuspid aortic valve (BAV) correlates with valve dysfunction, aortopathy, and the likelihood of needing aortic valve surgery.
- - Researchers analyzed 695 BAV patients, finding that those with raphe experienced more moderate to severe aortic stenosis and a higher prevalence of aortopathy, particularly Type B, compared to those without raphe.
- - The results indicated that having raphe significantly raises the odds of requiring aortic valve surgery within three years, highlighting the importance of monitoring patients with this anatomical feature.
Article Synopsis
- The ARCANGELO study evaluates the safety and effectiveness of cangrelor, an intravenous P2Y inhibitor, in patients with acute coronary syndrome (ACS) during and after percutaneous coronary intervention (PCI) while transitioning to oral P2Y inhibitors.
- In the study, 995 out of 1004 analyzed patients had a high percentage of ST-segment elevation myocardial infarction, with most undergoing PCI via radial access and receiving drug-eluting stents; bleeding events were low at 5.2% within 30 days post-procedure.
- The findings confirm that cangrelor is a safe and effective option for ACS patients undergoing PCI, with successful transition to oral P2
Background: During the COVID-19 pandemic, the risk of SARS-CoV-2 infection, the public health measures of social distancing, the freedom limitations, quarantine, and the enforced homeworking under the lockdown period, as well as medical causes including COVID-19 infection per se, may have caused major emotional distress, especially in the most vulnerable patients. We aimed to evaluate the variations in the number of admissions due to Takotsubo syndrome (TTS) during the COVID-19 pandemic in the Veneto region. Methods: We retrospectively reviewed and analyzed the number of admissions because of TTS in 13 Divisions of Cardiology located in the Veneto region, the northeastern area of Italy, covering a population of more than 2.
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- The study analyzed hospitalization trends for acute coronary syndrome (ACS) and other acute cardiovascular conditions in the Veneto Region of Italy during the COVID-19 pandemic, comparing data from 2020 to data from 2018 and 2019.
- Researchers found a significant reduction in ACS cases by 27.3% to 32% during the pandemic compared to the historical data, and a similar decrease of 36.5% to 40.6% in acute cardiovascular hospitalizations.
- The study concluded that this decline in hospitalizations could lead to undiagnosed cardiovascular issues, which may increase future morbidity and mortality rates for these conditions.