Research on Piscirickettsia salmonis, a critical pathogen affecting salmon aquaculture, has been hampered by inadequate host models to study the infection process in vivo. Here, we highlight zebrafish as a surrogate host model for in-depth analysis of P. salmonis infection by using fluorescent dyes and protein markers to visualize host-pathogen interactions.
View Article and Find Full Text PDFFacial Plast Surg Aesthet Med
January 2025
Parent-child interaction therapy (PCIT) is a highly efficacious, evidence-based treatment for children with disruptive behaviors and their families. PCIT is a dyadic therapy designed to improve parent-child relationships and decrease children's behavioral problems. PCIT research specific to Black families is currently sparse.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
In 2015, the largest recorded harmful algal bloom (HAB) occurred in the Northeast Pacific, causing nearly 100 million dollars in damages to fisheries and killing many protected marine mammals. Dominated by the toxic diatom , this bloom produced high levels of the neurotoxin domoic acid (DA). Through molecular and transcriptional characterization of 52 near-weekly phytoplankton net-tow samples collected at a bloom hotspot in Monterey Bay, California, we identified active transcription of known DA biosynthesis () genes from the three identified toxigenic species, including as the primary origin of toxicity.
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