Background: The three-dimensional nuclear arrangement of chromatin impacts many cellular processes operating at the DNA level in animal and plant systems. Chromatin organization is a dynamic process that can be affected by biotic and abiotic stresses. Three-dimensional imaging technology allows to follow these dynamic changes, but only a few semi-automated processing methods currently exist for quantitative analysis of the 3D chromatin organization.
View Article and Find Full Text PDFFor the past century, the nucleus has been the focus of extensive investigations in cell biology. However, many questions remain about how its shape and size are regulated during development, in different tissues, or during disease and aging. To track these changes, microscopy has long been the tool of choice.
View Article and Find Full Text PDFNucleusJ 1.0, an ImageJ plugin, is a useful tool to analyze nuclear morphology and chromatin organization in plant and animal cells. NucleusJ 2.
View Article and Find Full Text PDFMany instruments exist for measuring grip strength. The Jamar hydraulic hand dynamometer is currently the gold standard. The Labin is a prototype electronic dynamometer that can also measure maximum grip strength.
View Article and Find Full Text PDFWe present a new method to segment a cardiac RT3D ultrasound volume by integrating the registered segmentation of a cardiac cine-MR series in short axis of the same patient. The motivation behind our method is to improve the ultrasound segmentation process by integrating a reference shape built using the cine-MR segmentation on the same patient. As a side effect we obtain a close registration of the cine MR short axis slices with respect to the ultrasound volume.
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