Background: Global populations are aging, and the numbers of stroke survivors is increasing. Consequently, the need for caregiver support has increased. Because of this and demographic and socioeconomic changes, foreign caregivers are increasingly in demand in many developed countries.
View Article and Find Full Text PDFChronic diabetic wound poses a pressing global healthcare challenge, necessitating an approach to address issues such as pathogenic bacteria elimination, blood sugar regulation, and angiogenesis stimulation. Herein, we engineered a BiWO@CuO-GOx bio-heterojunction (BWCG bio-HJ) with exceptional cascade catalytic performance and impressive sonosensitivity to remodel the wound microenvironment and expedite the diabetic wound healing. Specifically, the Z-scheme junctions of BiWO@CuO significantly augmented carrier separation dynamics, leading to the highly efficient generation of reactive oxygen species (ROS) upon US irradiations.
View Article and Find Full Text PDFCooperative control of intersection signals and connected automated vehicles (CAVs) possess the potential for safety enhancement and congestion alleviation, facilitating the integration of CAVs into urban intelligent transportation systems. This research proposes an innovative deep reinforcement learning-based (DRL) cooperative control framework, including signal and speed modules, to dynamically adapt signal timing and CAV velocities for traffic safety and efficiency optimization. Among the DRL-based signal modules, a traffic state prediction model is merged with the current state to augment characteristics and the agent-learning process.
View Article and Find Full Text PDFAngiopoietin-2, an important contributor to angiogenesis and vascular remodeling, is increasingly recognized in kidney research. This review explores clinical insights and experimental perspectives on angiopoietin-2 in kidney diseases. Traditionally seen as an antagonist of the Tie-2, which is a receptor tyrosine kinase of endothelial cells and some hematopoietic stem cells, angiopoietin-2 exerts both proangiogenic and antiangiogenic effects, making it a versatile and context-dependent player in kidney pathophysiology.
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