Publications by authors named "F Cecchin"
Article Synopsis
- Progressive cardiac conduction defects, often linked to specific gene variants in SCN5A and CACNA1D, can cause sinoatrial node dysfunction.
- Researchers created an induced pluripotent stem cell line from a 13-year-old patient with conduction system disease and ventricular tachycardia, carrying variants in SCN5A, CACNA1D, and DSP.
- The iPSC line showed characteristics of pluripotency, effectively differentiated into all three embryonic germ layers, and maintained normal genetics, paving the way for understanding cardiac arrhythmias and developing personalized treatments.
Background: Thromboembolic events related to invasive electrophysiology studies, while rare, can have devastating consequences. Use of systemic anticoagulation for a pediatric or adult-congenital invasive electrophysiology study is recommended, however there is no established standard of practice in this population.
Objective: To report on procedural practices for thromboembolism prophylaxis during invasive electrophysiology studies for pediatric patients and adults with congenital heart disease.
Phenytoin is a versatile drug with utility in neurological, dermatological, and even cardiac disease processes. Though phenytoin is widely available due to its excellent anti-epileptic properties, it is now rarely used as an antiarrhythmic. Phenytoin has well-studied sodium-channel blocking abilities which can be taken advantage of to treat ventricular arrhythmias.
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