Publications by authors named "F Caza"

Marine ecosystems are under escalating threats from myriad environmental stressors, necessitating a deeper understanding of their impact on biodiversity and the health of sentinel organisms. In this study, we carried out a spatiotemporal multi-omic analysis of liquid biopsies collected from mussels (Mytilus spp.) in marine ecosystems of a national park.

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  • - Oocysts of Toxoplasma gondii found in cat feces can contaminate coastal waters, where they attach to algae and accumulate in bivalves; studies were conducted in the Kerguelen and Galapagos archipelagos to assess this contamination.
  • - In the Galapagos, high cat density (142 per km) led to 15.38% of oysters testing positive for T. gondii, while in Kerguelen, lower cat density (1-3 per km) resulted in a higher percentage (40.83%) of mussels testing positive.
  • - The research suggests that oocysts can spread several kilometers from their source and that environmental factors, like currents and kelp forests
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  • Blue mussels are important indicators of ecosystem health due to their abundance and stable presence in polar coastal areas, which allows for monitoring biodiversity and species interactions.
  • The study utilized liquid biopsy technology and Oxford Nanopore's portable sequencing platform to analyze the cell-free DNA in blue mussels, revealing significant biodiversity from various organisms in the marine ecosystem.
  • The results highlight differences in nuclear and mitochondrial DNA distributions among sampling sites, demonstrating the ONT platform's effectiveness for fieldwork in conservation and resource management efforts in remote environments.
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Establishing long-term microbiome-based monitoring programs is critical for managing and conserving wild fish populations in response to climate change. In most cases, these studies have been conducted on gut and, to a lesser extent, skin (mucus) microbiomes. Here, we exploited the concept of liquid biopsy to study the circulating bacterial microbiome of two Northern halibut species of economic and ecological importance.

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Liquid biopsy (LB) is a concept that is rapidly gaining ground in the biomedical field. Its concept is largely based on the detection of circulating cell-free DNA (ccfDNA) fragments that are mostly released as small fragments following cell death in various tissues. A small percentage of these fragments are from foreign (nonself) tissues or organisms.

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