Publications by authors named "F Cavigioli"

Importance: Preventive efforts in pregnancy-related alloimmunization have considerably decreased the prevalence of hemolytic disease of the fetus and newborn (HDFN). International studies are therefore essential to obtain a deeper understanding of the postnatal management and outcomes of HDFN. Taken together with numerous treatment options, large practice variations among centers may exist.

View Article and Find Full Text PDF
Article Synopsis
  • Bloody stools in newborns can indicate various conditions, including idiopathic neonatal transient colitis, food-protein-induced allergic proctocolitis (FPIAP), and necrotizing enterocolitis (NEC), with distinct treatments and prognoses for each.
  • A study of pre-term infants in the NICU revealed that NEC patients had lower eosinophil counts and higher procalcitonin levels, as well as more severe abdominal ultrasound and X-ray findings compared to those with FPIAP or transient colitis.
  • Differentiating between idiopathic neonatal transient colitis and FPIAP is difficult without lab markers or imaging, so confirmation of FPIAP requires an oral food challenge
View Article and Find Full Text PDF

Introduction: Intrauterine transfusion is the treatment for fetal anemia resulting from maternal alloimmunization, infections (parvovirus B19 and cytomegalovirus), single demise of a monochorionic twin, chorioangioma, and other rare conditions. Fetal analgesia is mandatory to reduce movement and pain perception during the procedure. This study aims to evaluate perinatal outcomes for such procedures, following the routine use of fetal analgesia in our clinical practice.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates the effectiveness of two surfactant administration methods—INtubate-RECruit-SURfactant-Extubate (IN-REC-SUR-E) and less invasive surfactant administration (LISA)—on improving BPD-free survival in preterm infants with respiratory distress syndrome (RDS).
  • A total of 382 preterm infants, born at 24-27 weeks' gestation and not intubated at birth, will be randomly assigned to either method within the first 24 hours of life. The primary outcome being measured is a combination of death or bronchopulmonary dysplasia (BPD) at 36 weeks' postmenstrual age.
View Article and Find Full Text PDF

Coagulase-negative staphylococci (CoNS) are reportedly responsible for 50-60% of bloodstream infections in very preterm (<1500 g) infants in neonatal intensive care units (NICUs). is an increasingly prevalent pathogen in the neonatal setting, frequently causing central-line-associated bloodstream infections (CLABSIs) that can be difficult to eradicate. Central venous catheter (CVC) removal versus in situ treatment with CoNS CLABSIs is a controversial treatment strategy with no clear consensus.

View Article and Find Full Text PDF