Publications by authors named "F Castellana"

Introduction: Latest epidemiological metrics put a global prevalence of 20.6 million people suffering from spinal cord injury (SCI), leading to a burden of functional disability, deterioration in quality of life and reduced life expectancy. A thorough statement of diagnostic methods and treatment protocols for swallowing disorders after SCI stands as a major priority to streamline patient care and cost-sharing.

View Article and Find Full Text PDF

This systematic review investigates the potential of bergamot, a polyphenol-rich citrus fruit, in improving osteosarcopenic obesity, a condition characterized by the simultaneous presence of osteoporosis, obesity, and sarcopenia. Bergamot extracts have been suggested to possess several pharmacological properties, including anti-inflammatory and antioxidant effects, which could be useful in the management of age-related diseases and neuromuscular health. The review highlights the promising effects of bergamot extracts on skeletal muscle mass and function, particularly in the context of obesity, metabolic syndrome, osteosarcopenic obesity, and osteoporosis.

View Article and Find Full Text PDF

Background: Mediterranean diet may enhance cognitive function and delay the progression of Alzheimer's disease (AD). We conducted a systematic review to investigate the effect of oleocanthal (OC) from extra-virgin olive oil (EVOO) on amyloid-β (Aβ) burden in preclinical models of AD, considering the anti-inflammatory and neuroprotective effects of EVOO biophenols, which are key components of the Mediterranean dietary model.

Methods: The literature was searched through six electronic databases until February 2023.

View Article and Find Full Text PDF
Article Synopsis
  • This study systematically reviews the link between air pollution and female ovarian reserve, based on 15 human observational studies selected from 136 articles.
  • Findings indicate a significant inverse relationship between ovarian reserve and environmental pollutants, particularly PM2.5, PM10, and nitrogen oxides (NO), while evidence for other pollutants like benzene and formaldehyde was minimal.
  • Despite evidence suggesting that air pollutants negatively impact ovarian reserve, the overall quality of the studies is moderate, highlighting the need for further research to establish causality.
View Article and Find Full Text PDF

Polyphenols are secondary metabolites found in plants, foods, and drinks, occurring in small quantities and showcasing antioxidant and anti-inflammatory qualities. The primary polyphenols consist of flavonoids, phenolic acids, stilbenes, and lignans. However, there is currently no comprehensive quantitative analysis of epidemiological data on overall death rates.

View Article and Find Full Text PDF