Publications by authors named "F Carrilho"
Background: Cholangiocarcinoma (CCA) represents a global health challenge, with rising incidence and mortality rates. This study aimed to elucidate the clinical course and practices of CCA in Latin America.
Methods: This observational cohort study investigated individuals diagnosed with CCA between 2010 and 2023 at five referral centres across Latin America.
Article Synopsis
- * In group 1 (44 patients with acute hepatitis A), 4% tested positive for HEV IgM and 14.5% for IgG, while in group 2 (47 patients with non-A-C AH), these rates were 4.3% for IgM and 14.9% for IgG; only one sample from group 2 tested positive for HEV RNA.
- * The findings suggest HEV should be considered in non-A-C acute hepatitis cases, particularly as one patient with HEV recently traveled to a high-serop
Development of HepatIA: A computed tomography annotation platform and database for artificial intelligence training in hepatocellular carcinoma detection at a Brazilian tertiary teaching hospital.
Clinics (Sao Paulo)
October 2024
Article Synopsis
- - The study addresses the high mortality rates associated with hepatocellular carcinoma (HCC) and discusses the importance of CT scans in diagnosing this condition, highlighting the role of AI in medical imaging, which is limited by a lack of accessible liver imaging datasets.
- - The researchers developed HepatIA, a specialized medical imaging annotation platform that organizes data from 656 patient CT scans, using technologies like PostgreSQL, Django, and Vue.js, while also employing advanced annotation tools for accurate liver morphology analysis.
- - The resulting HepatIA database includes data from both healthy individuals and those with liver diseases, with a user-friendly interface that allows for detailed demographic searches, ultimately facilitating deep learning research on liver lesions within the medical community.
Objectives: The primary objective was to evaluate Liver-Related Events (LREs), including hepatic decompensation (ascites, hemorrhagic varices and encephalopathy) and Hepatocellular Carcinoma (HCC), as well as changes in liver stiffness during the follow-up period among patients who achieved a Sustained Virological Response (SVR) after treatment for chronic Hepatitis C Virus (HCV) infection.
Methods: A total of 218 patients with HCV were treated, and those who achieved an SVR were followed up for 3-years. Transient Elastography (TE) using FibroScan® was performed at various time points: before treatment, at the end of treatment, at 6-months post-treatment, at 1-year post-treatment, at 2-years post-treatment, and at 3-years post-treatment.