Publications by authors named "F Carlsen"

Article Synopsis
  • Waiting times in publicly funded healthcare aim to provide equal access but often show that wealthier individuals wait less.
  • Studies that look at socioeconomic status usually use broad area-based measures, which can lead to misleading conclusions.
  • By analyzing socioeconomic status at three different levels (individual, population cell, and municipal), the research finds that individual-level data presents a less pronounced socioeconomic gradient in waiting times compared to aggregate data, suggesting that researchers relying solely on aggregate data might exaggerate these disparities.
View Article and Find Full Text PDF

The potato family includes a highly diverse cultivar repertoire and has a high potential for nutritional yield improvement and refinement but must in line with other crops be adapted to biotic and abiotic stresses, for example, accelerated by climate change and environmental demands. The combination of pluripotency, high ploidy, and relative ease of protoplast isolation, transformation, and regeneration together with clonal propagation through tubers makes potato highly suitable for precise genetic engineering. Most potato varieties are tetraploid having a very high prevalence of length polymorphisms and small nucleotide polymorphisms between alleles, often complicating CRISPR-Cas editing designs and strategies.

View Article and Find Full Text PDF

Background: Continuity in the general practitioner (GP)-patient relationship is associated with better healthcare outcomes. However, few studies have examined the impact of permanent discontinuities on all listed patients when a GP retires or relocates.

Aim: To investigate changes in the Norwegian population's overall healthcare use and mortality after discontinuity due to Regular GPs retiring or relocating.

View Article and Find Full Text PDF

Continued climate change impose multiple stressors on crops, including pathogens, salt, and drought, severely impacting agricultural productivity. Innovative solutions are necessary to develop resilient crops. Here, using quantitative potato proteomics, we identify Parakletos, a thylakoid protein that contributes to disease susceptibility.

View Article and Find Full Text PDF

is a wild diploid tuber-bearing plant. We here demonstrate transgene-free genome editing of protoplasts and regeneration of gene-edited plants. We use ribonucleoproteins, consisting of Cas9 and sgRNA, assembled in vitro, to target a gene belonging to the nitrate and peptide transporter family.

View Article and Find Full Text PDF