Publications by authors named "F Carl van Wyk"

Background: There is currently limited evidence regarding the potential complications of sphenopalatine artery ligation. The post-operative outcomes at two secondary care centres over a 10-year period were reviewed.

Methods: A retrospective review was undertaken of patients undergoing emergency and elective sphenopalatine artery ligation between January 2011 and January 2021.

View Article and Find Full Text PDF

Background: Sepsis is a life-threatening condition with high mortality rates. Early detection and treatment are critical to improving outcomes. Our primary objective was to develop artificial intelligence capable of predicting sepsis earlier using a minimal set of streaming physiological data in real time.

View Article and Find Full Text PDF

This paper presents a novel method for hierarchical analysis of machine learning algorithms to improve predictions of at risk patients, thus further enabling prompt therapy. Specifically, we develop a multi-layer machine learning approach to analyze continuous, high-frequency data. We illustrate the capabilities of this approach for early identification of patients at risk of sepsis, a potentially life-threatening complication of an infection, using high-frequency (minute-by-minute) physiological data collected from bedside monitors.

View Article and Find Full Text PDF

Purpose: Sepsis is a life-threatening condition with high mortality rates and expensive treatment costs. To improve short- and long-term outcomes, it is critical to detect at-risk sepsis patients at an early stage.

Methods: A data-set consisting of high-frequency physiological data from 1161 critically ill patients was analyzed.

View Article and Find Full Text PDF