Publications by authors named "F Caner"

Article Synopsis
  • The study aimed to compare the distribution of the ACE I/D polymorphism in laryngeal cancer patients versus a control group and its relevance to clinical parameters related to the cancer.
  • A total of 44 laryngeal cancer patients and 61 healthy controls were genotyped using the PCR-RFLP method, and statistical analyses revealed no significant differences in ACE genotypes between the two groups.
  • While ACE genotypes did not influence overall cancer prevalence, the presence of the ACE DD genotype was linked to a higher risk of lymph node metastasis in patients.
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Although there exists a vast literature on the dynamic comminution or fragmentation of rocks, concrete, metals, and ceramics, none of the known models suffices for macroscopic dynamic finite element analysis. This paper outlines the basic idea of the macroscopic model. Unlike static fracture, in which the driving force is the release of strain energy, here the essential idea is that the driving force of comminution under high-rate compression is the release of the local kinetic energy of shear strain rate.

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Although the mechanical behaviour of the human annulus fibrosus has been extensively studied, the interaction between the collagen fibres and the ground matrix has not been well understood and is therefore ignored by most constitutive models. The objective of this study is to identify the significance of the fibre-matrix interaction in the human annulus fibrosus by careful investigation of the experimental data, the theoretical constitutive models, and the numerical simulation results in the literature. Based on the experimental results from biaxial and uniaxial tests, it is shown that the mechanical behaviour of the matrix can be well simulated by an incompressible neo-Hookean type model, but the effective stiffness of the matrix depends on fibre stretch ratio, which can only be explained by fibre-matrix interaction.

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In a recent paper, Peng et al. (2006, "An Anisotropic Hyperelastic Constitutive Model With Fiber-Matrix Interaction for the Human Annulus Fibrosis," ASME J. Appl.

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This paper presents a nonlinearly elastic anisotropic microplane formulation in 3D for computational constitutive modeling of arterial soft tissue in the passive regime. The constitutive modeling of arterial (and other biological) soft tissue is crucial for accurate finite element calculations, which in turn are essential for design of implants, surgical procedures, bioartificial tissue, as well as determination of effect of progressive diseases on tissues and implants. The model presented is defined at a lower scale (mesoscale) than the conventional macroscale and it incorporates the effect of all the (collagen) fibers which are anisotropic structural components distributed in all directions within the tissue material in addition to that of isotropic bulk tissue.

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