[The ethnopharmacology of hallucinogens: from "primitive rites" to their "presence" on TV. Proposals for the year 2000].

Hallucinogens are the chemicals which in nontoxic doses produce changes in perception, mental confusion, memory loss, or disorientation for person, place and time, with organic brain reactions. Mescaline and LSD are historically the most interesting hallucinogens. Today the cannabis is very important, socially.

[After the benzodiazepines].

After the diazepines, new agents have appeared: sleep-inducing cyclopyrrolones, pure anxiolytic serotoninergic agents such as buspirone or 5HT2 antagonists such as ritanserine, there is also renewed interest for beta-blockers and alpha 2-adrenergic agonists, calcium blocking agents and some NMDA blockers.

[Drug therapy and affective disorders: state of the art].

Different types of depression require adequate treatment. From the most recent MAO inhibitors we go on to tricyclic antidepressants, to the second generation (amoxapine, buspirone, venlafaxine), and to selective inhibitors of 5HT reuptake (fluoxetine and its derivates, again venlafaxine, sertaline). Indications for lithium remain unchanged.