Publications by authors named "F C Tulunay"

Aim: The aim of this article was to evaluate the influence of different demand-side measures to enhance the prescribing of generics in ambulatory care based on cross-national comparisons.

Methods: An observational retrospective study was conducted using administrative databases from across Europe, documenting changes in reimbursed utilization and expenditure of different proton pump inhibitors (PPIs) and statins between 2001 and 2007, alongside different reforms to enhance prescribing efficiency. Utilization was converted to defined daily doses (DDDs) and expenditures were converted to euros.

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Pharmaceutical expenditures in ambulatory care rose rapidly in Europe in the 1990s and early 2000s. This was typically faster than other components of healthcare spending, leading to reforms to moderate future growth. A number of these centered on generic medicines with measures to lower reimbursed prices as well as enhance their prescribing and dispensing.

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Introduction: European countries need to learn from each other to address unsustainable increases in pharmaceutical expenditures.

Objective: To assess the influence of the many supply and demand-side initiatives introduced across Europe to enhance prescribing efficiency in ambulatory care. As a result provide future guidance to countries.

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Article Synopsis
  • - Osteoarthritis (OA) primarily affects older adults, who may experience more side effects from traditional oral anti-inflammatory medications; therefore, this study examines the safety and effectiveness of topical nimesulide.
  • - In a double-blind, placebo-controlled trial with 74 knee OA patients, the treatment group applied topical nimesulide gel three times daily for 30 days while the placebo group used a similar-looking gel.
  • - Results showed significant improvements in overall OA symptoms and satisfaction in the nimesulide group compared to placebo, indicating that topical nimesulide can enhance quality of life for knee OA patients.
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Migraine is a common disorder with a relatively high burden of disease from the perspective of both society and the individual patient. Optimizing the use of prophylactic treatment may decrease the frequency and severity of attacks thus reducing the burden of disease. In this regard, topiramate has been found to be as effective as propranolol in the prevention of migraine attacks.

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